Harmonizome 3.0

G patch domain containing 2

The gene encodes a nuclear factor that may play a role in spermatogenesis and in tumor growth during breast cancer. The encoded protein contains a G-patch domain with an RNA binding motif. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2017]

angiogenic factor with G patch and FHA domains 1 pseudogene 10

G patch domain and KOW motifs

This gene encodes a putative RNA-binding protein containing G-patch and KOW (Kyprides, Ouzounis, Woese) domains. The encoded protein interacts directly with protein kinase A and protein kinase X and is also found associated with the spliceosome. [provided by RefSeq, Aug 2013]

angiogenic factor with G patch and FHA domains 1 pseudogene

angiogenic factor with G patch and FHA domains 1

This gene encodes an angiogenic factor that promotes proliferation of endothelial cells. Mutations in this gene are associated with a susceptibility to Klippel-Trenaunay syndrome. Pseudogenes of this gene are found on chromosomes 3, 4, 10 and 16.[provided by RefSeq, Sep 2010]

zinc finger, CCCH-type with G patch domain

Enables DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in negative regulation of epidermal growth factor-activated receptor activity and negative regulation of transcription by RNA polymerase II. Located in nucleoplasm and plasma membrane. [provided by Alliance of Genome Resources, Mar 2025]

G patch domain containing 2-like

Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Mar 2025]

G patch domain containing 11

Predicted to enable nucleic acid binding activity. Located in kinetochore. [provided by Alliance of Genome Resources, Mar 2025]

angiogenic factor with G patch and FHA domains 1 pseudogene 3

angiogenic factor with G patch and FHA domains 1 pseudogene 2

angiogenic factor with G patch and FHA domains 1 pseudogene 1

angiogenic factor with G patch and FHA domains 1 pseudogene 7

angiogenic factor with G patch and FHA domains 1 pseudogene 5

angiogenic factor with G patch and FHA domains 1 pseudogene 4

angiogenic factor with G patch and FHA domains 1 pseudogene 9

angiogenic factor with G patch and FHA domains 1 pseudogene 8

SURP and G patch domain containing 2

This gene encodes a member of the arginine/serine-rich family of splicing factors. The encoded protein functions in mRNA processing. Alternatively spliced transcript variants have been described. [provided by RefSeq, Feb 2009]

SURP and G patch domain containing 1

SF4 is a member of the SURP family of splicing factors.[supplied by OMIM, Sep 2003]

angiogenic factor with G patch and FHA domains 1 pseudogene

G patch domain and ankyrin repeats 1

This gene is located in a cluster of HLA-B-associated transcripts, which is included in the human major histocompatability complex III region. This gene encodes a protein which is thought to play a role in immunity. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Nov 2010]

G patch domain containing 3

Predicted to enable nucleic acid binding activity. Involved in negative regulation of RIG-I signaling pathway; negative regulation of type I interferon production; and positive regulation of DNA-templated transcription. Located in cytosol and nucleoplasm. [provided by Alliance of Genome Resources, Mar 2025]

angiogenic factor with G patch and FHA domains 1-like

angiogenic factor with G patch and FHA domains 1-like

G patch domain containing 8

The protein encoded by this gene contains an RNA-processing domain, a zinc finger domain, a lysine-rich region and a serine-rich region. A mutation in the serine-rich region of the protein is thought to be associated with hyperuricemia (PMID: 21594610). Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Feb 2015]

G patch domain containing 4

Enables RNA binding activity. Predicted to act upstream of or within hematopoietic progenitor cell differentiation. Located in nucleolus and nucleoplasm. [provided by Alliance of Genome Resources, Mar 2025]

G patch domain containing 1

Predicted to enable RNA binding activity. Predicted to be involved in mRNA splicing, via spliceosome. Part of catalytic step 2 spliceosome. [provided by Alliance of Genome Resources, Mar 2025]