Name

PFN2 Gene

profilin 2

The protein encoded by this gene is a ubiquitous actin monomer-binding protein belonging to the profilin family. It is thought to regulate actin polymerization in response to extracellular signals. There are two alternatively spliced transcript variants encoding different isoforms described for this gene. [provided by RefSeq, Jul 2008]

PFN3 Gene

profilin 3

The product of this gene belongs to the profilin family of proteins. This protein binds to actin and affects the structure of the cytoskeleton. It also may be involved in spermatogenesis. It is a single exon gene. [provided by RefSeq, Jul 2008]

PFN4 Gene

profilin family, member 4

Predicted to enable actin monomer binding activity. Predicted to be involved in sequestering of actin monomers and spermatid development. Predicted to be located in cytoplasm. Predicted to be active in cell cortex. [provided by Alliance of Genome Resources, Mar 2025]

PFN1P12 Gene

profilin 1 pseudogene 12

PFN1P11 Gene

profilin 1 pseudogene 11

PFN1P10 Gene

profilin 1 pseudogene 10

MYPOP Gene

Myb-related transcription factor, partner of profilin

Predicted to enable DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Mar 2025]

PFN1 Gene

profilin 1

This gene encodes a member of the profilin family of small actin-binding proteins. The encoded protein plays an important role in actin dynamics by regulating actin polymerization in response to extracellular signals. Deletion of this gene is associated with Miller-Dieker syndrome, and the encoded protein may also play a role in Huntington disease. Multiple pseudogenes of this gene are located on chromosome 1. [provided by RefSeq, Jul 2012]

PFN1P9 Gene

profilin 1 pseudogene 9

PFN1P8 Gene

profilin 1 pseudogene 8

PFN1P3 Gene

profilin 1 pseudogene 3

PFN1P2 Gene

profilin 1 pseudogene 2

PFN1P1 Gene

profilin 1 pseudogene 1

PFN1P6 Gene

profilin 1 pseudogene 6

PFN1P4 Gene

profilin 1 pseudogene 4

LOC102724437 Gene

profilin-1-like