Results for "RUNX3 regulates p14-ARF": 5 genes

Name

RUNX3 Gene

runt-related transcription factor 3

This gene encodes a member of the runt domain-containing family of transcription factors. A heterodimer of this protein and a beta subunit forms a complex that binds to the core DNA sequence 5'-PYGPYGGT-3' found in a number of enhancers and promoters, and can either activate or suppress transcription. It also interacts with other transcription factors. It functions as a tumor suppressor, and the gene is frequently deleted or transcriptionally silenced in cancer. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016]

FRA7C Gene

fragile site, aphidicolin type, common, fra(7)(p14.2)

FRA5E Gene

fragile site, aphidicolin type, common, fra(5)(p14)

FRA11D Gene

fragile site, aphidicolin type, common, fra(11)(p14.2)

DEL11P15P14 Gene

Chromosome 11p15-p14 deletion syndrome