Name

XRRA1 Gene

X-ray radiation resistance associated 1

Involved in response to X-ray. Located in cytoplasm and nuclear body. [provided by Alliance of Genome Resources, Mar 2025]

UVRAG Gene

UV radiation resistance associated

This gene complements the ultraviolet sensitivity of xeroderma pigmentosum group C cells and encodes a protein with a C2 domain. The protein activates the Beclin1-PI(3)KC3 complex, promoting autophagy and suppressing the proliferation and tumorigenicity of human colon cancer cells. Chromosomal aberrations involving this gene are associated with left-right axis malformation and mutations in this gene have been associated with colon cancer. [provided by RefSeq, Jul 2008]

RSCIS Gene

Radiation sensitivity/chromosome instability syndrome, autosomal dominant