Harmonizome 3.0

meiosis/spermiogenesis associated 1

Predicted to be involved in cell differentiation. Predicted to act upstream of or within manchette assembly and protein localization. Predicted to be located in cytosol and manchette. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Mar 2025]

spindlin family, member 2A

This gene encodes one of three members of the DXF34 gene family, located in a 100-kb region of chromosome Xp11.21. [provided by RefSeq, Nov 2009]

spindlin family, member 2B

Enables methylated histone binding activity. Predicted to be involved in regulation of DNA-templated transcription. Located in cytosol and nucleoplasm. [provided by Alliance of Genome Resources, Mar 2025]

spindlin family, member 4

Enables methylated histone binding activity. Involved in negative regulation of cell population proliferation and positive regulation of canonical Wnt signaling pathway. Located in chromatin; cytoplasm; and nucleus. [provided by Alliance of Genome Resources, Mar 2025]

spindlin 1

Enables histone reader activity and methylated histone binding activity. Involved in positive regulation of DNA-templated transcription; positive regulation of Wnt signaling pathway; and rRNA transcription. Located in cytosol and nucleus. [provided by Alliance of Genome Resources, Mar 2025]

spindlin family, member 3

Enables methylated histone binding activity. Predicted to be involved in regulation of DNA-templated transcription. Predicted to be located in membrane. Predicted to be active in cytosol and nucleoplasm. [provided by Alliance of Genome Resources, Mar 2025]

spindlin family, member 2B pseudogene

spindlin interactor and repressor of chromatin binding

Involved in DNA damage response and negative regulation of DNA-templated transcription. Is active in nucleus and site of DNA damage. [provided by Alliance of Genome Resources, Mar 2025]