Name

SYMPK Gene

symplekin

This gene encodes a nuclear protein that functions in the regulation of polyadenylation and promotes gene expression. The protein forms a high-molecular weight complex with components of the polyadenylation machinery. It is thought to serve as a scaffold for recruiting regulatory factors to the polyadenylation complex. It also participates in 3'-end maturation of histone mRNAs, which do not undergo polyadenylation. The protein also localizes to the cytoplasmic plaques of tight junctions in some cell types. [provided by RefSeq, Jul 2008]

Symplekin/Pta1 Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Symplekin/Pta1 protein domain from the InterPro Predicted Protein Domain Annotations dataset.

symplekin Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term symplekin in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Symplekin C-terminal Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Symplekin C-terminal protein domain from the InterPro Predicted Protein Domain Annotations dataset.