Harmonizome 3.0

MIF antisense RNA 1

macrophage migration inhibitory factor (glycosylation-inhibiting factor)

This gene encodes a lymphokine involved in cell-mediated immunity, immunoregulation, and inflammation. It plays a role in the regulation of macrophage function in host defense through the suppression of anti-inflammatory effects of glucocorticoids. This lymphokine and the JAB1 protein form a complex in the cytosol near the peripheral plasma membrane, which may indicate an additional role in integrin signaling pathways. [provided by RefSeq, Jul 2008]

dopachrome tautomerase

Predicted to enable dopachrome isomerase activity. Involved in response to blue light. Located in intracellular membrane-bounded organelle and plasma membrane. Implicated in oculocutaneous albinism. [provided by Alliance of Genome Resources, Mar 2025]

D-dopachrome tautomerase-like

D-dopachrome tautomerase pseudogene 1

D-dopachrome tautomerase

D-dopachrome tautomerase converts D-dopachrome into 5,6-dihydroxyindole. The DDT gene is related to the migration inhibitory factor (MIF) in terms of sequence, enzyme activity, and gene structure. DDT and MIF are closely linked on chromosome 22. [provided by RefSeq, Jul 2008]

D-dopachrome tautomerase-like

Predicted to enable phenylpyruvate tautomerase activity. Predicted to be involved in melanin biosynthetic process. Located in extracellular exosome. [provided by Alliance of Genome Resources, Mar 2025]