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Results for "Tribbles homologue 1": 3 genes, 37 gene sets

Name

TRIB1 Gene

tribbles pseudokinase 1

Enables RNA polymerase II-specific DNA-binding transcription factor binding activity; mitogen-activated protein kinase kinase binding activity; and protein kinase inhibitor activity. Involved in several processes, including JNK cascade; negative regulation of lipopolysaccharide-mediated signaling pathway; and regulation of protein kinase activity. Located in cytoplasm and nucleus. [provided by Alliance of Genome Resources, Mar 2025]

TRIB2 Gene

tribbles pseudokinase 2

This gene encodes one of three members of the Tribbles family. The Tribbles members share a Trb domain, which is homologous to protein serine-threonine kinases, but lacks the active site lysine and probably lacks a catalytic function. The Tribbles proteins interact and modulate the activity of signal transduction pathways in a number of physiological and pathological processes. This Tribbles member induces apoptosis of cells mainly of the hematopoietic origin. It has been identified as a protein up-regulated by inflammatory stimuli in myeloid (THP-1) cells, and also as an oncogene that inactivates the transcription factor C/EBPalpha (CCAAT/enhancer-binding protein alpha) and causes acute myelogenous leukemia. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Mar 2009]

TRIB3 Gene

tribbles pseudokinase 3

The protein encoded by this gene is a putative protein kinase that is induced by the transcription factor NF-kappaB. The encoded protein is a negative regulator of NF-kappaB and can also sensitize cells to TNF- and TRAIL-induced apoptosis. In addition, this protein can negatively regulate the cell survival serine-threonine kinase AKT1. Differential promoter usage and alternate splicing result in multiple transcript variants. [provided by RefSeq, Jul 2014]

Tribbles homologue 1 Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Tribbles homologue 1 protein domain from the InterPro Predicted Protein Domain Annotations dataset.

tribbles Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term tribbles in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Pseudokinase tribbles family/serine-threonine-protein kinase 40 Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Pseudokinase tribbles family/serine-threonine-protein kinase 40 protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Pseudokinase tribbles, TRB3 Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Pseudokinase tribbles, TRB3 protein domain from the InterPro Predicted Protein Domain Annotations dataset.

homologue Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term homologue in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

DNA mismatch repair protein MutS-homologue MSH6 Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the DNA mismatch repair protein MutS-homologue MSH6 protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Activator of Hsp90 ATPase homologue 1-like Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Activator of Hsp90 ATPase homologue 1-like protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Disabled homologue 2-interacting protein Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Disabled homologue 2-interacting protein protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Eyes absent homologue 4 Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Eyes absent homologue 4 protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Eyes absent homologue 3 Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Eyes absent homologue 3 protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Eyes absent homologue 2 Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Eyes absent homologue 2 protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Eyes absent homologue 1 Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Eyes absent homologue 1 protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Alkylated DNA repair protein AlkB, homologue 8, N-terminal Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Alkylated DNA repair protein AlkB, homologue 8, N-terminal protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Protein phosphatase Slingshot homologue 1 Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Protein phosphatase Slingshot homologue 1 protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Protein Unc-13 homologue C Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Protein Unc-13 homologue C protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Teashirt homologue 1 Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Teashirt homologue 1 protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Protein strawberry notch homologue 2 Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Protein strawberry notch homologue 2 protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Formin, protein diaphanous homologue 1 Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Formin, protein diaphanous homologue 1 protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Formin, protein diaphanous homologue 3 Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Formin, protein diaphanous homologue 3 protein domain from the InterPro Predicted Protein Domain Annotations dataset.

DnaJ homologue subfamily C member 3 Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the DnaJ homologue subfamily C member 3 protein domain from the InterPro Predicted Protein Domain Annotations dataset.

KIAA1430 homologue Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the KIAA1430 homologue protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Lethal giant larvae homologue 2 Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Lethal giant larvae homologue 2 protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Williams-Beuren syndrome chromosomal region 28 protein homologue Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Williams-Beuren syndrome chromosomal region 28 protein homologue protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Monensin-resistant homologue 2 Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Monensin-resistant homologue 2 protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Teashirt homologue 3 Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Teashirt homologue 3 protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Teashirt homologue 2 Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Teashirt homologue 2 protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Mitochondrial import receptor subunit TOM6 homologue Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Mitochondrial import receptor subunit TOM6 homologue protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Protein notum homologue Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Protein notum homologue protein domain from the InterPro Predicted Protein Domain Annotations dataset.

DnaJ homologue subfamily C member 10 Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the DnaJ homologue subfamily C member 10 protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Retinoic acid-induced protein 2/sine oculis-binding protein homologue Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Retinoic acid-induced protein 2/sine oculis-binding protein homologue protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Mitochondrial import receptor subunit TOM5 homologue Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Mitochondrial import receptor subunit TOM5 homologue protein domain from the InterPro Predicted Protein Domain Annotations dataset.

NFU1 iron-sulfur cluster scaffold homologue Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the NFU1 iron-sulfur cluster scaffold homologue protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Lon protease homologue 2, peroxisomal Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Lon protease homologue 2, peroxisomal protein domain from the InterPro Predicted Protein Domain Annotations dataset.

WASP homologue-associated protein with actin, membranes and microtubules Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the WASP homologue-associated protein with actin, membranes and microtubules protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Protein diaphanous homologue 2 Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Protein diaphanous homologue 2 protein domain from the InterPro Predicted Protein Domain Annotations dataset.

DnaJ homologue, subfamily C, member 28, conserved domain Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the DnaJ homologue, subfamily C, member 28, conserved domain protein domain from the InterPro Predicted Protein Domain Annotations dataset.

tRNA-splicing ligase RtcB homologue, eukaryotic Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the tRNA-splicing ligase RtcB homologue, eukaryotic protein domain from the InterPro Predicted Protein Domain Annotations dataset.