Harmonizome 3.0

maternally expressed 3 (non-protein coding)

This gene is a maternally expressed imprinted gene. Multiple alternatively spliced transcript variants have been transcribed from this gene and all of them are long non-coding RNAs (lncRNAs). This gene is expressed in many normal tissues, but its expression is lost in multiple cancer cell lines of various tissue origins. It inhibits tumor cell proliferation in vitro. It also interacts with the tumor suppressor p53, and regulates p53 target gene expression. Its deletion enhances angiogenesis in vivo. Many experimental evidences demonstrate that this gene is a lncRNA tumor suppressor. [provided by RefSeq, Mar 2012]

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term meg3 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

From Rummagene Transcription Factor Associations 2026

target genes of the PMC12178829-mmc4.xlsx-Sheet_3-MEG3-KD_Down-ID_AR transcription factor from the Rummagene Transcription Factor Associations 2026 dataset.

From Rummagene Transcription Factor Associations 2026

target genes of the PMC12178829-mmc4.xlsx-Sheet_3-MEG3-KD_Down-GeneName_AR transcription factor from the Rummagene Transcription Factor Associations 2026 dataset.

From Rummagene Transcription Factor Associations 2026

target genes of the PMC12178829-mmc4.xlsx-Sheet_4-MEG3-KD_Up-ID_AR transcription factor from the Rummagene Transcription Factor Associations 2026 dataset.

From Rummagene Transcription Factor Associations 2026

target genes of the PMC12178829-mmc4.xlsx-Sheet_4-MEG3-KD_Up-GeneName_AR transcription factor from the Rummagene Transcription Factor Associations 2026 dataset.