| Name |
|---|
LOC390956 Genepeptidyl-prolyl cis-trans isomerase A pseudogene |
LOC101927654 Genepeptidyl-prolyl cis-trans isomerase A pseudogene |
LOC105374327 Genepeptidyl-prolyl cis-trans isomerase A pseudogene |
LOC100996503 Genepeptidyl-prolyl cis-trans isomerase A pseudogene |
LOC105371242 Genepeptidyl-prolyl cis-trans isomerase A-like 4G Predicted to enable cyclosporin A binding activity and peptidyl-prolyl cis-trans isomerase activity. Predicted to be involved in protein folding. Predicted to be active in cytoplasm. [provided by Alliance of Genome Resources, Mar 2025] |
PTRH2 Genepeptidyl-tRNA hydrolase 2 The protein encoded by this gene is a mitochondrial protein with two putative domains, an N-terminal mitochondrial localization sequence, and a UPF0099 domain. In vitro assays suggest that this protein possesses peptidyl-tRNA hydrolase activity, to release the peptidyl moiety from tRNA, thereby preventing the accumulation of dissociated peptidyl-tRNA that could reduce the efficiency of translation. This protein also plays a role regulating cell survival and death. It promotes survival as part of an integrin-signaling pathway for cells attached to the extracellular matrix (ECM), but also promotes apoptosis in cells that have lost their attachment to the ECM, a process called anoikos. After loss of cell attachment to the ECM, this protein is phosphorylated, is released from the mitochondria into the cytosol, and promotes caspase-independent apoptosis through interactions with transcriptional regulators. This gene has been implicated in the development and progression of tumors, and mutations in this gene have been associated with an infantile multisystem neurologic, endocrine, and pancreatic disease (INMEPD) characterized by intellectual disability, postnatal microcephaly, progressive cerebellar atrophy, hearing impairment, polyneuropathy, failure to thrive, and organ fibrosis with exocrine pancreas insufficiency (PMID: 25574476). Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Mar 2015] |
PTRH1 Genepeptidyl-tRNA hydrolase 1 homolog (S. cerevisiae) Enables aminoacyl-tRNA hydrolase activity. Involved in rescue of stalled ribosome. Located in mitochondrion. [provided by Alliance of Genome Resources, Mar 2025] |
LOC101060458 Genepeptidyl-prolyl cis-trans isomerase A-like |
LOC101928610 Genepeptidyl-prolyl cis-trans isomerase A pseudogene |
LOC105374236 Genepeptidyl-prolyl cis-trans isomerase A pseudogene |
LOC101928624 Genepeptidyl-prolyl cis-trans isomerase A pseudogene |
LOC100287361 Genepeptidyl-prolyl cis-trans isomerase A pseudogene |
LOC105369232 Genepeptidyl-prolyl cis-trans isomerase FKBP4 pseudogene |
LOC101060363 Genepeptidyl-prolyl cis-trans isomerase A pseudogene |
LOC101926910 Genepeptidyl-prolyl cis-trans isomerase A pseudogene |
LOC442744 Genepeptidyl-prolyl cis-trans isomerase A pseudogene |
LOC105378561 Genepeptidyl-prolyl cis-trans isomerase A pseudogene |
ACE3P Geneangiotensin I converting enzyme (peptidyl-dipeptidase A) 3, pseudogene Predicted to be located in acrosomal vesicle. [provided by Alliance of Genome Resources, Mar 2025] |
LOC100996727 Genepeptidyl-prolyl cis-trans isomerase A pseudogene |
PTRHD1 Genepeptidyl-tRNA hydrolase domain containing 1 This gene encodes the enzyme peptidyl-tRNA hydrolase. Peptidyl-tRNA hydrolases perform the essential function of recycling peptidyl-tRNAs. Mutations in this gene are associated with autosomal-recessive intellectual disability and parkinsonism. [provided by RefSeq, May 2017] |
LOC101927689 Genepeptidyl-prolyl cis-trans isomerase A pseudogene |
LOC101928064 Genepeptidyl-prolyl cis-trans isomerase A pseudogene |
