skull base meningioma

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Results for "skull base meningioma": 10 genes

Name
SPTLC1P1 Gene serine palmitoyltransferase, long chain base* subunit 1 pseudogene 1*
SPTLC1P2 Gene serine palmitoyltransferase, long chain base* subunit 1 pseudogene 2*
SPTLC1P5 Gene serine palmitoyltransferase, long chain base* subunit 1 pseudogene 5*
SPTLC1P4 Gene serine palmitoyltransferase, long chain base* subunit 1 pseudogene 4*
SPTLC2 Gene serine palmitoyltransferase, long chain base* subunit 2* This gene encodes a long chain base subunit of serine palmitoyltransferase. Serine palmitoyltransferase, which consists of two different subunits, is the key enzyme in sphingolipid biosynthesis. It catalyzes the pyridoxal-5-prime-phosphate-dependent condensation of L-serine and palmitoyl-CoA to 3-oxosphinganine. Mutations in this gene were identified in patients with hereditary sensory neuropathy type I. [provided by RefSeq, Mar 2011]
SPTLC3 Gene serine palmitoyltransferase, long chain base* subunit 3* This gene encodes a subunit of the serine palmitoyltransferase complex which catalyzes the rate-limiting step in sphingolipid biosynthesis. This subunit metabolizes lauroyl- and myristoyl-CoA and generates C14 and C16-sphingoid bases. [provided by RefSeq, Mar 2017]
SPTLC1 Gene serine palmitoyltransferase, long chain base* subunit 1* This gene encodes a member of the class-II pyridoxal-phosphate-dependent aminotransferase family. The encoded protein is the long chain base subunit 1 of serine palmitoyltransferase. Serine palmitoyltransferase converts L-serine and palmitoyl-CoA to 3-oxosphinganine with pyridoxal 5'-phosphate and is the key enzyme in sphingolipid biosynthesis. Mutations in this gene were identified in patients with hereditary sensory neuropathy type 1. Alternatively spliced variants encoding different isoforms have been identified. Pseudogenes of this gene have been defined on chromosomes 1, 6, 10, and 13. [provided by RefSeq, Jul 2013]
LOC100422263 Gene serine palmitoyltransferase, long chain base* subunit 2 pseudogene*
SPTLC1P3 Gene serine palmitoyltransferase, long chain base* subunit 1 pseudogene 3*
BMT2 Gene base methyltransferase of 25S rRNA 2 homolog Enables S-adenosyl-L-methionine binding activity. Involved in cellular response to amino acid starvation; cellular response to methionine; and positive regulation of TORC1 signaling. Predicted to be located in cytosol. [provided by Alliance of Genome Resources, Mar 2025]