Results for "sorbitol catabolic process": 4 genes

Name

LOC100419644 Gene

sorbitol dehydrogenase pseudogene

SORD Gene

sorbitol dehydrogenase

Sorbitol dehydrogenase (SORD; EC 1.1.1.14) catalyzes the interconversion of polyols and their corresponding ketoses, and together with aldose reductase (ALDR1; MIM 103880), makes up the sorbitol pathway that is believed to play an important role in the development of diabetic complications (summarized by Carr and Markham, 1995 [PubMed 8535074]). The first reaction of the pathway (also called the polyol pathway) is the reduction of glucose to sorbitol by ALDR1 with NADPH as the cofactor. SORD then oxidizes the sorbitol to fructose using NAD(+) cofactor.[supplied by OMIM, Jul 2010]

SORD2P Gene

sorbitol dehydrogenase 2, pseudogene

SORDL Gene

sorbitol dehydrogenase-like