Results for "zymogen binding": 3 genes

Name

GP2 Gene

glycoprotein 2 (zymogen granule membrane)

This gene encodes an integral membrane protein that is secreted from intracellular zymogen granules and associates with the plasma membrane via glycosylphosphatidylinositol (GPI) linkage. The encoded protein binds pathogens such as enterobacteria, thereby playing an important role in the innate immune response. The C-terminus of this protein is related to the C-terminus of the protein encoded by the neighboring gene, uromodulin (UMOD). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015]

ZG16B Gene

zymogen granule protein 16B

Predicted to enable carbohydrate binding activity. Involved in cell migration. Located in apicolateral plasma membrane; cytoplasm; and extracellular region. [provided by Alliance of Genome Resources, Mar 2025]

ZG16 Gene

zymogen granule protein 16

Predicted to enable carbohydrate binding activity and peptidoglycan binding activity. Predicted to be involved in protein transport. Predicted to act upstream of or within defense response to Gram-positive bacterium and suppression of symbiont entry into host. Located in Golgi lumen and collagen-containing extracellular matrix. [provided by Alliance of Genome Resources, Mar 2025]