Name

APLF Gene

aprataxin and PNKP like factor

Enables several functions, including ADP-D-ribose modification-dependent protein binding activity; nuclease activity; and poly-ADP-D-ribose binding activity. Involved in DNA repair; DNA repair-dependent chromatin remodeling; and protein localization to chromatin. Acts upstream of or within positive regulation of DNA ligation. Located in nucleoplasm. Is active in site of double-strand break. [provided by Alliance of Genome Resources, Mar 2025]

aplf Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term aplf in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

APLF Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for APLF from the Pathway Commons Protein-Protein Interactions dataset.

Protein of unknown function DUF2228, C2H2, APLF-like Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Protein of unknown function DUF2228, C2H2, APLF-like protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Zinc finger, C2H2, APLF-like Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Zinc finger, C2H2, APLF-like protein domain from the InterPro Predicted Protein Domain Annotations dataset.