Name

SASH1 Gene

SAM and SH3 domain containing 1

This gene encodes a scaffold protein involved in the TLR4 signaling pathway that may stimulate cytokine production and endothelial cell migration in response to invading pathogens. The encoded protein has also been described as a potential tumor suppressor that may negatively regulate proliferation, apoptosis, and invasion of cancer cells, and reduced expression of this gene has been observed in multiple human cancers. Mutations in this gene may be associated with abnormal skin pigmentation in human patients. [provided by RefSeq, Oct 2016]

BL8710 (SASH1) Gene Set

From NURSA Protein Complexes

proteins in the BL8710 (SASH1) protein complex recovered by IP-MS from the NURSA Protein Complexes dataset.

SASH1 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for SASH1 from the Pathway Commons Protein-Protein Interactions dataset.