Harmonizome 3.0

corticotropin releasing hormone receptor 2

The protein encoded by this gene belongs to the G-protein coupled receptor 2 family, and the subfamily of corticotropin releasing hormone receptor. This receptor shows high affinity for corticotropin releasing hormone (CRH), and also binds CRH-related peptides such as urocortin. CRH is synthesized in the hypothalamus, and plays an important role in coordinating the endocrine, autonomic, and behavioral responses to stress and immune challenge. Studies in mice suggest that this receptor maybe involved in mediating cardiovascular homeostasis. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.[provided by RefSeq, Jan 2011]

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term crhr2 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

From Pathway Commons Protein-Protein Interactions

interacting proteins for CRHR2 from the Pathway Commons Protein-Protein Interactions dataset.

From HuBMAP Azimuth Cell Type Annotations

genes associated with the Human - Motor Cortex - Cluster - PVALB+ SST CRHR2+ Layer 5-6 GABAergic neuron cell type from the HuBMAP Azimuth Cell Type Annotations dataset.

From HuBMAP Azimuth Cell Type Annotations

genes associated with the Mouse - Motor Cortex - Cluster - Sst+ Crhr2+ GABAergic neuron_1 cell type from the HuBMAP Azimuth Cell Type Annotations dataset.

From HuBMAP Azimuth Cell Type Annotations

genes associated with the Mouse - Motor Cortex - Cluster - Sst+ Crhr2+ GABAergic neuron_2 cell type from the HuBMAP Azimuth Cell Type Annotations dataset.

From HuBMAP ASCT+B Annotations

biomarker genes for the Brain_CT2_Inh L5-6 PVALB SST CRHR2 cell type from the HuBMAP ASCT+B dataset.

From HuBMAP ASCT+B Augmented with RNA-seq Coexpression

biomarker genes for the Brain_CT2_Inh L5-6 PVALB SST CRHR2 cell type from the HuBMAP ASCT+B Augmented with RNA-seq Coexpression dataset.