Condensation of Prophase Chromosomes

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Results for "Condensation of Prophase Chromosomes": 14 genes

Name
RCBTB2P1 Gene regulator of chromosome condensation* (RCC1) and BTB (POZ) domain containing protein 2 pseudogene 1*
RCC1 Gene regulator of chromosome condensation* 1* Enables several functions, including guanyl-nucleotide exchange factor activity; nucleosomal DNA binding activity; and protein heterodimerization activity. Involved in G1/S transition of mitotic cell cycle; regulation of mitotic nuclear division; and spindle organization. Located in chromatin; cytoplasm; and nuclear lumen. Part of protein-containing complex. [provided by Alliance of Genome Resources, Mar 2025]
RCC2 Gene regulator of chromosome condensation* 2* The protein encoded by this gene is a guanine exchange factor that is active on RalA, a small GTPase. The encoded protein and RalA are both essential for proper kinetochore-microtubule function in early mitosis. This protein has been shown to be a biomarker for colorectal cancer. [provided by RefSeq, Oct 2016]
RCC2P1 Gene regulator of chromosome condensation* 2 pseudogene 1*
RCC2P2 Gene regulator of chromosome condensation* 2 pseudogene 2*
RCC2P3 Gene regulator of chromosome condensation* 2 pseudogene 3*
RCC2P4 Gene regulator of chromosome condensation* 2 pseudogene 4*
RCC2P5 Gene regulator of chromosome condensation* 2 pseudogene 5*
RCC2P6 Gene regulator of chromosome condensation* 2 pseudogene 6*
RCC2P7 Gene regulator of chromosome condensation* 2 pseudogene 7*
RCC2P8 Gene regulator of chromosome condensation* 2 pseudogene 8*
ACIN1 Gene apoptotic chromatin condensation* inducer 1* Apoptosis is defined by several morphologic nuclear changes, including chromatin condensation and nuclear fragmentation. This gene encodes a nuclear protein that induces apoptotic chromatin condensation after activation by caspase-3, without inducing DNA fragmentation. This protein has also been shown to be a component of a splicing-dependent multiprotein exon junction complex (EJC) that is deposited at splice junctions on mRNAs, as a consequence of pre-mRNA splicing. It may thus be involved in mRNA metabolism associated with splicing. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Oct 2011]
RCBTB2 Gene regulator of chromosome condensation* (RCC1) and BTB (POZ) domain containing protein 2* This gene encodes a protein containing two C-terminal BTB/POZ domains that is related to regulator of chromosome condensation (RCC). The encoded protein may act as a guanine nucleotide exchange factor. This gene is observed to be lost or underexpressed in prostate cancers. There is a pseudogene of this gene on chromosome 10. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2013]
RCBTB1 Gene regulator of chromosome condensation* (RCC1) and BTB (POZ) domain containing protein 1* This gene encodes a protein with an N-terminal RCC1 domain and a C-terminal BTB (broad complex, tramtrack and bric-a-brac) domain. In rat, over-expression of this gene in vascular smooth muscle cells induced cellular hypertrophy. In rat, the C-terminus of RCBTB1 interacts with the angiotensin II receptor-1A. In humans, this gene maps to a region of chromosome 13q that is frequently deleted in B-cell chronic lymphocytic leukemia and other lymphoid malignancies. [provided by RefSeq, Jul 2008]