| Name |
|---|
DCC GeneDCC netrin 1 receptor This gene encodes a netrin 1 receptor. The transmembrane protein is a member of the immunoglobulin superfamily of cell adhesion molecules, and mediates axon guidance of neuronal growth cones towards sources of netrin 1 ligand. The cytoplasmic tail interacts with the tyrosine kinases Src and focal adhesion kinase (FAK, also known as PTK2) to mediate axon attraction. The protein partially localizes to lipid rafts, and induces apoptosis in the absence of ligand. The protein functions as a tumor suppressor, and is frequently mutated or downregulated in colorectal cancer and esophageal carcinoma. [provided by RefSeq, Oct 2009] |
LOC343052 Geneimmunoglobulin superfamily, DCC subclass, member 3 pseudogene |
IGDCC3 Geneimmunoglobulin superfamily, DCC subclass, member 3 Predicted to be involved in cell-cell adhesion. Predicted to act upstream of or within neuromuscular process controlling balance. Predicted to be located in membrane. [provided by Alliance of Genome Resources, Mar 2025] |
IGDCC4 Geneimmunoglobulin superfamily, DCC subclass, member 4 Predicted to be involved in cell-cell adhesion. Predicted to be located in plasma membrane. [provided by Alliance of Genome Resources, Mar 2025] |
LOC105371448 Geneimmunoglobulin superfamily DCC subclass member 3-like |
LOC100631370 Geneimmunoglobulin superfamily, DCC subclass, member 3 pseudogene |
