Harmonizome 3.0

dynamin 1 pseudogene 17

dynamin-1-like

dynamin 1 pseudogene 48

dynamin 1 pseudogene 43

dynamin 1 pseudogene 41

dynamin 1 pseudogene 40

dynamin 1 pseudogene 47

dynamin 1 pseudogene 46

dynamin 1 pseudogene 45

dynamin 1 pseudogene 44

dynamin 1 pseudogene 18

dynamin 1 pseudogene 19

dynamin 1 pseudogene 50

dynamin 1 pseudogene 49

dynamin 1 pseudogene 5

MX dynamin-like GTPase 1 pseudogene

dynamin 1 pseudogene

MX dynamin-like GTPase 2

The protein encoded by this gene has a nuclear and a cytoplasmic form and is a member of both the dynamin family and the family of large GTPases. The nuclear form is localized in a granular pattern in the heterochromatin region beneath the nuclear envelope. A nuclear localization signal (NLS) is present at the amino terminal end of the nuclear form but is lacking in the cytoplasmic form due to use of an alternate translation start codon. This protein is upregulated by interferon-alpha but does not contain the antiviral activity of a similar myxovirus resistance protein 1. [provided by RefSeq, Jul 2008]

MX dynamin-like GTPase 1

This gene encodes a guanosine triphosphate (GTP)-metabolizing protein that participates in the cellular antiviral response. The encoded protein is induced by type I and type II interferons and antagonizes the replication process of several different RNA and DNA viruses. There is a related gene located adjacent to this gene on chromosome 21, and there are multiple pseudogenes located in a cluster on chromosome 4. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]

dynamin 1 pseudogene 34

Predicted to enable GTP binding activity and GTPase activity. [provided by Alliance of Genome Resources, Mar 2025]

dynamin 1 pseudogene 38

dynamin 1 pseudogene 39

dynamin 1 pseudogene 36

dynamin 1 pseudogene 37

dynamin 1 pseudogene 35

dynamin 1 pseudogene 32

dynamin 1 pseudogene 33

dynamin 1 pseudogene 30

dynamin 1 pseudogene 31

dynamin 1 pseudogene 9

dynamin 1

This gene encodes a member of the dynamin subfamily of GTP-binding proteins. The encoded protein possesses unique mechanochemical properties used to tubulate and sever membranes, and is involved in clathrin-mediated endocytosis and other vesicular trafficking processes. Actin and other cytoskeletal proteins act as binding partners for the encoded protein, which can also self-assemble leading to stimulation of GTPase activity. More than sixty highly conserved copies of the 3' region of this gene are found elsewhere in the genome, particularly on chromosomes Y and 15. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]

dynamin 3

This gene encodes a member of a family of guanosine triphosphate (GTP)-binding proteins that associate with microtubules and are involved in vesicular transport. The encoded protein functions in the development of megakaryocytes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2013]

dynamin 2

Dynamins represent one of the subfamilies of GTP-binding proteins. These proteins share considerable sequence similarity over the N-terminal portion of the molecule, which contains the GTPase domain. Dynamins are associated with microtubules. They have been implicated in cell processes such as endocytosis and cell motility, and in alterations of the membrane that accompany certain activities such as bone resorption by osteoclasts. Dynamins bind many proteins that bind actin and other cytoskeletal proteins. Dynamins can also self-assemble, a process that stimulates GTPase activity. Five alternatively spliced transcripts encoding different proteins have been described. Additional alternatively spliced transcripts may exist, but their full-length nature has not been determined. [provided by RefSeq, Jun 2010]

dynamin 1-like

This gene encodes a member of the dynamin superfamily of GTPases. The encoded protein mediates mitochondrial and peroxisomal division, and is involved in developmentally regulated apoptosis and programmed necrosis. Dysfunction of this gene is implicated in several neurological disorders, including Alzheimer's disease. Mutations in this gene are associated with the autosomal dominant disorder, encephalopathy, lethal, due to defective mitochondrial and peroxisomal fission (EMPF). Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jun 2013]

dynamin binding protein

This gene encodes a protein belonging to the guanine nucleotide exchange factor family, and which regulates the configuration of cell junctions. It contains multiple binding sites for dynamin and thus links dynamin to actin regulatory proteins. Polymorphisms in this gene have been linked to Alzheimer's disease in some populations, though there are conflicting reports of such linkages in other populations. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]

MX dynamin-like GTPase 1 pseudogene

MX dynamin-like GTPase 1 pseudogene

dynamin-1 pseudogene

dynamin 1 pseudogene 25

dynamin 1 pseudogene 24

dynamin 1 pseudogene 27

dynamin 1 pseudogene 26

dynamin 1 pseudogene 29

dynamin 1 pseudogene 28