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GHRH Genegrowth hormone releasing hormone This gene encodes a member of the glucagon family of proteins. The encoded preproprotein is produced in the hypothalamus and cleaved to generate the mature factor, known as somatoliberin, which acts to stimulate growth hormone release from the pituitary gland. Variant receptors for somatoliberin have been found in several types of tumors, and antagonists of these receptors can inhibit the growth of the tumors. Defects in this gene are a cause of dwarfism, while hypersecretion of the encoded protein is a cause of gigantism. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed. [provided by RefSeq, Jan 2016] |
ghrh Gene SetFrom GeneRIF Biological Term Annotations genes co-occuring with the biological term ghrh in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset. |
GHRH Gene SetFrom Guide to Pharmacology Protein Ligands of Receptors receptors of the GHRH ligand (protein) from the curated Guide to Pharmacology Protein Ligands of Receptors dataset. |
GHRH Gene SetFrom Pathway Commons Protein-Protein Interactions interacting proteins for GHRH from the Pathway Commons Protein-Protein Interactions dataset. |
elevated response to ghrh by pituitary somatotrophinomas Gene SetFrom GAD Gene-Disease Associations genes associated with the disease elevated response to ghrh by pituitary somatotrophinomas in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset. |
GHRH-(1-29)-OH (human) Gene SetFrom Guide to Pharmacology Chemical Ligands of Receptors receptors of the GHRH-(1-29)-OH (human) ligand (chemical) from the curated Guide to Pharmacology Chemical Ligands of Receptors dataset. |
[125I]GHRH (human) Gene SetFrom Guide to Pharmacology Chemical Ligands of Receptors receptors of the [125I]GHRH (human) ligand (chemical) from the curated Guide to Pharmacology Chemical Ligands of Receptors dataset. |
GHRH-(1-29)-NH2 (human) Gene SetFrom Guide to Pharmacology Chemical Ligands of Receptors receptors of the GHRH-(1-29)-NH2 (human) ligand (chemical) from the curated Guide to Pharmacology Chemical Ligands of Receptors dataset. |
[Ac-Tyr1 D-Arg2]GHRH-(1-29)-NH2 (human) Gene SetFrom Guide to Pharmacology Chemical Ligands of Receptors receptors of the [Ac-Tyr1 D-Arg2]GHRH-(1-29)-NH2 (human) ligand (chemical) from the curated Guide to Pharmacology Chemical Ligands of Receptors dataset. |
GHRH-(1-29)-NH2 (rat) Gene SetFrom Guide to Pharmacology Chemical Ligands of Receptors receptors of the GHRH-(1-29)-NH2 (rat) ligand (chemical) from the curated Guide to Pharmacology Chemical Ligands of Receptors dataset. |