Name

PENK Gene

proenkephalin

This gene encodes a preproprotein that is proteolytically processed to generate multiple protein products. These products include the pentapeptide opioids Met-enkephalin and Leu-enkephalin, which are stored in synaptic vesicles, then released into the synapse where they bind to mu- and delta-opioid receptors to modulate the perception of pain. Other non-opioid cleavage products may function in distinct biological activities. [provided by RefSeq, Jul 2015]

Proenkephalin B Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Proenkephalin B protein domain from the InterPro Predicted Protein Domain Annotations dataset.

proenkephalin Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term proenkephalin in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Proenkephalin A Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Proenkephalin A protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Opioid proenkephalin pathway Gene Set

From PANTHER Pathways

proteins participating in the Opioid proenkephalin pathway pathway from the PANTHER Pathways dataset.