Harmonizome 3.0

carboxymethylenebutenolidase homolog (Pseudomonas)

CMBL (EC 3.1.1.45) is a cysteine hydrolase of the dienelactone hydrolase family that is highly expressed in liver cytosol. CMBL preferentially cleaves cyclic esters, and it activates medoxomil-ester prodrugs in which the medoxomil moiety is linked to an oxygen atom (Ishizuka et al., 2010 [PubMed 20177059]).[supplied by OMIM, Apr 2010]

carboxymethylenebutenolidase homolog (Pseudomonas) pseudogene

From DisGeNET Gene-Disease Associations

genes associated with the disease Pseudomonas Aeroginosa in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

From CTD Gene-Disease Associations

genes/proteins associated with the disease Pseudomonas Infections from the curated CTD Gene-Disease Associations dataset.

From GAD Gene-Disease Associations

genes associated with the disease bronchiectasis; cystic fibrosis; pseudomonas infections; staphylococcal infections in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

From GAD Gene-Disease Associations

genes associated with the disease pulmonary function; nitric oxide; pseudomonas aeruginosa infection in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

From GAD Gene-Disease Associations

genes associated with the disease child nutrition disorders; cystic fibrosis; pseudomonas infections; respiratory tract infections in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

From GAD Gene-Disease Associations

genes associated with the disease cystic fibrosis; pseudomonas infections in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

From GAD Gene-Disease Associations

genes associated with the disease cystic fibrosis; exocrine pancreatic insufficiency; pseudomonas infections in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

From GAD Gene-Disease Associations

genes associated with the disease cystic fibrosis; lung diseases; pseudomonas infections in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

From GAD Gene-Disease Associations

genes associated with the disease cystic fibrosis; disease susceptibility; pseudomonas infections in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

From GAD Gene-Disease Associations

genes associated with the disease pseudomonas infections; recurrence; rhinitis; sinusitis in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

From GAD Gene-Disease Associations

genes associated with the disease bacterial infections; burkholderia infections; cystic fibrosis; pseudomonas infections; recurrence; respiratory tract infections in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

From GAD Gene-Disease Associations

genes associated with the disease cystic fibrosis; diabetes mellitus; pseudomonas infections in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

From GAD Gene-Disease Associations

genes associated with the disease burkholderia infections; cystic fibrosis; pseudomonas infections in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term pseudomonas in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

From GEO Signatures of Differentially Expressed Genes for Diseases

genes differentially expressed during Pseudomonas Infection_Lung Tissue_GSE923 disease perturbation from the GEO Signatures of Differentially Expressed Genes for Diseases dataset.

From GEO Signatures of Differentially Expressed Genes for Small Molecules

genes differentially expressed following the ciprofloxacin_pseudomonas aeruginosa; pseudomonas aeruginosa pao1_gpl84_gse12678 small molecule perturbation from the GEO Signatures of Differentially Expressed Genes for Small Molecules dataset.

From HuGE Navigator Gene-Phenotype Associations

genes associated with the Pseudomonas Infections phenotype by text-mining GWAS publications from the HuGE Navigator Gene-Phenotype Associations dataset.

From OMIM Gene-Disease Associations

genes associated with the {pseudomonas aeruginosa, susceptibility to chronic infection by, in cystic fibrosis} phenotype from the curated OMIM Gene-Disease Associations dataset.

From DisGeNET Gene-Disease Associations

genes associated with the disease Pseudomonas Aeruginosa Infection in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

From ClinVar Gene-Phenotype Associations 2025

genes associated with the Pseudomonas aeruginosa phenotype from the curated ClinVar Gene-Phenotype Associations 2025 dataset.