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Results for "drb3": 1 gene, 2 gene sets

Name

HLA-DRB3 Gene

major histocompatibility complex, class II, DR beta 3

HLA-DRB3 belongs to the HLA class II beta chain paralogues. This class II molecule is a heterodimer consisting of an alpha (DRA) and a beta (DRB) chain, both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells. The beta chain is approximately 26-28 kDa and its gene contains 6 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, exon 4 encodes the transmembrane domain and exon 5 encodes the cytoplasmic tail. Within the DR molecule the beta chain contains all the polymorphisms specifying the peptide binding specificities. Typing for these polymorphisms is routinely done for bone marrow and kidney transplantation. There are multiple pseudogenes of this gene. [provided by RefSeq, Feb 2020]

drb3 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term drb3 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

HLA-DRB3 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for HLA-DRB3 from the Pathway Commons Protein-Protein Interactions dataset.