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Results for "otulin": 2 genes, 3 gene sets

Name

OTULIN Gene

OTU deubiquitinase with linear linkage specificity

This gene encodes a member of the peptidase C65 family of ubiquitin isopeptidases. Members of this family remove ubiquitin from proteins. The encoded enzyme specifically recognizes and removes M1(Met1)-linked, or linear, ubiquitin chains from protein substrates. Linear ubiquitin chains are known to regulate the NF-kappa B signaling pathway in the context of immunity and inflammation. Mutations in this gene cause a potentially fatal autoinflammatory syndrome in human patients. [provided by RefSeq, Sep 2016]

OTULIN-DT Gene

OTULIN divergent transcript

otulin Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term otulin in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

OTULIN Gene Set

From CM4AI KOLF21J CRISPRi Gene Perturbation Atlas

genes differentially expressed following the OTULIN gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

Otulin-Related Autoinflammatory Syndrome Gene Set

From DisGeNET Gene-Disease Associations

genes associated with the disease Otulin-Related Autoinflammatory Syndrome in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.