Harmonizome 3.0

insulin-like 4 (placenta)

INSL4 encodes the insulin-like 4 protein, a member of the insulin superfamily. INSL4 encodes a precursor that undergoes post-translational cleavage to produce 3 polypeptide chains, A-C, that form tertiary structures composed of either all three chains, or just the A and B chains. Expression of INSL4 products occurs within the early placental cytotrophoblast and syncytiotrophoblast. [provided by RefSeq, Jul 2008]

placenta-specific 1

Involved in placenta development. Predicted to be located in extracellular region. [provided by Alliance of Genome Resources, Mar 2025]

placenta-specific 4

Predicted to be located in plasma membrane. [provided by Alliance of Genome Resources, Mar 2025]

placenta-specific 9

Predicted to be located in extracellular region. [provided by Alliance of Genome Resources, Mar 2025]

placenta-specific 8

Predicted to enable chromatin binding activity. Predicted to be involved in positive regulation of cold-induced thermogenesis and positive regulation of transcription by RNA polymerase II. Predicted to act upstream of or within several processes, including brown fat cell differentiation; defense response to bacterium; and response to cold. Predicted to be located in azurophil granule lumen and extracellular region. [provided by Alliance of Genome Resources, Mar 2025]

placenta expressed transcript 1

Predicted to be involved in negative regulation of cell-matrix adhesion; positive regulation of cell migration; and wound healing, spreading of epidermal cells. Predicted to be located in extracellular region and plasma membrane. Predicted to be active in apical plasma membrane and external side of plasma membrane. [provided by Alliance of Genome Resources, Mar 2025]

placenta-specific 9 pseudogene

Predicted to be located in extracellular region. [provided by Alliance of Genome Resources, Mar 2025]

testis, prostate and placenta expressed

Predicted to be involved in flagellated sperm motility. Predicted to be located in cytoplasm; cytoskeleton; and motile cilium. Predicted to be active in axonemal A tubule inner sheath and sperm flagellum. [provided by Alliance of Genome Resources, Mar 2025]