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S100A12 GeneS100 calcium binding protein A12 The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein is proposed to be involved in specific calcium-dependent signal transduction pathways and its regulatory effect on cytoskeletal components may modulate various neutrophil activities. The protein includes an antimicrobial peptide which has antibacterial activity. [provided by RefSeq, Nov 2014] |
s100a12 Gene SetFrom GeneRIF Biological Term Annotations genes co-occuring with the biological term s100a12 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset. |
S100A12 Gene SetFrom Pathway Commons Protein-Protein Interactions interacting proteins for S100A12 from the Pathway Commons Protein-Protein Interactions dataset. |
S100A12 Gene SetFrom LINCS L1000 CMAP CRISPR Knockout Consensus Signatures genes differentially expressed following the S100A12 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset. |