Harmonizome 3.0

microRNA 769

microRNAs (miRNAs) are short (20-24 nt) non-coding RNAs that are involved in post-transcriptional regulation of gene expression in multicellular organisms by affecting both the stability and translation of mRNAs. miRNAs are transcribed by RNA polymerase II as part of capped and polyadenylated primary transcripts (pri-miRNAs) that can be either protein-coding or non-coding. The primary transcript is cleaved by the Drosha ribonuclease III enzyme to produce an approximately 70-nt stem-loop precursor miRNA (pre-miRNA), which is further cleaved by the cytoplasmic Dicer ribonuclease to generate the mature miRNA and antisense miRNA star (miRNA*) products. The mature miRNA is incorporated into a RNA-induced silencing complex (RISC), which recognizes target mRNAs through imperfect base pairing with the miRNA and most commonly results in translational inhibition or destabilization of the target mRNA. The RefSeq represents the predicted microRNA stem-loop. [provided by RefSeq, Sep 2009]

From COSMIC Cell Line Gene CNV Profiles

genes with high or low copy number in 769-P relative to other cell lines from the COSMIC Cell Line Gene CNV Profiles dataset.

From COSMIC Cell Line Gene Mutation Profiles

genes mutated in the 769-P cell line from the COSMIC Cell Line Gene Mutation Profiles dataset.

From Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles

genes with high or low copy number in 769-P relative to other cell lines from the Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles dataset.

From Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles

genes with high or low expression in 769-P relative to other cell lines from the Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles dataset.

From Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles

genes mutated in the 769-P cell line from the Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles dataset.

From Sanger Dependency Map Cancer Cell Line Proteomics

proteins associated with the cell line 769-P from the Sanger Dependency Map Cancer Cell Line Proteomics dataset.

From MiRTarBase microRNA Targets

target genes of the hsa-miR-769-3p microRNA in low- or high-throughput microRNA targeting studies from the MiRTarBase microRNA Targets dataset.

From MiRTarBase microRNA Targets

target genes of the hsa-miR-769-5p microRNA in low- or high-throughput microRNA targeting studies from the MiRTarBase microRNA Targets dataset.

From TargetScan Predicted Conserved microRNA Targets

target genes of the hsa-miR-769-5p microRNA predicted using conserved miRNA seed sequences from the TargetScan Predicted Conserved microRNA Targets dataset.

From TargetScan Predicted Conserved microRNA Targets

target genes of the hsa-miR-769-3p microRNA predicted using conserved miRNA seed sequences from the TargetScan Predicted Conserved microRNA Targets dataset.

From TargetScan Predicted Nonconserved microRNA Targets

target genes of the hsa-miR-769-5p microRNA predicted using nonconserved miRNA seed sequences from the TargetScan Predicted Nonconserved microRNA Targets dataset.

From TargetScan Predicted Nonconserved microRNA Targets

target genes of the hsa-miR-769-3p microRNA predicted using nonconserved miRNA seed sequences from the TargetScan Predicted Nonconserved microRNA Targets dataset.

From Rummagene Transcription Factor Associations 2026

target genes of the PMC10361959-41419_2023_5985_MOESM1_ESM.pdf-769-LYL1_LYL1 transcription factor from the Rummagene Transcription Factor Associations 2026 dataset.