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Results for "ABHD12": 1 gene, 3 gene sets

Name

ABHD12 Gene

abhydrolase domain containing 12

This gene encodes an enzyme that catalyzes the hydrolysis of 2-arachidonoyl glycerol (2-AG), the main endocannabinoid lipid transmitter that acts on cannabinoid receptors, CB1 and CB2. The endocannabinoid system is involved in a wide range of physiological processes, including neurotransmission, mood, appetite, pain appreciation, addiction behavior, and inflammation. Mutations in this gene are associated with the neurodegenerative disease, PHARC (polyneuropathy, hearing loss, ataxia, retinitis pigmentosa, and cataract), resulting from an inborn error of endocannabinoid metabolism. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.[provided by RefSeq, Jan 2011]

ABHD12 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for ABHD12 from the Pathway Commons Protein-Protein Interactions dataset.

ABHD12 Gene Set

From CM4AI KOLF21J CRISPRi Gene Perturbation Atlas

genes differentially expressed following the ABHD12 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

Monoacylglycerol lipase protein ABHD12 Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Monoacylglycerol lipase protein ABHD12 protein domain from the InterPro Predicted Protein Domain Annotations dataset.