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CDH11 Genecadherin 11, type 2, OB-cadherin (osteoblast) This gene encodes a type II classical cadherin from the cadherin superfamily, integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. Expression of this particular cadherin in osteoblastic cell lines, and its upregulation during differentiation, suggests a specific function in bone development and maintenance. [provided by RefSeq, Jul 2008] |
cdh11 Gene SetFrom GeneRIF Biological Term Annotations genes co-occuring with the biological term cdh11 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset. |
CDH11 Gene SetFrom MSigDB Cancer Gene Co-expression Modules co-expressed genes for CDH11 from the MSigDB Cancer Gene Co-expression Modules dataset. |
CDH11 Gene SetFrom Pathway Commons Protein-Protein Interactions interacting proteins for CDH11 from the Pathway Commons Protein-Protein Interactions dataset. |
CDH11 Gene SetFrom LINCS L1000 CMAP CRISPR Knockout Consensus Signatures genes differentially expressed following the CDH11 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset. |
CDH11 homotypic and heterotypic interactions Gene Setproteins participating in the CDH11 homotypic and heterotypic interactions pathway from the Reactome Pathways 2024 dataset. |
Regulation of CDH11 Expression and Function Gene Setproteins participating in the Regulation of CDH11 Expression and Function pathway from the Reactome Pathways 2024 dataset. |
Regulation of CDH11 function Gene Setproteins participating in the Regulation of CDH11 function pathway from the Reactome Pathways 2024 dataset. |
Regulation of CDH11 gene transcription Gene Setproteins participating in the Regulation of CDH11 gene transcription pathway from the Reactome Pathways 2024 dataset. |
Regulation of CDH11 mRNA translation by microRNAs Gene Setproteins participating in the Regulation of CDH11 mRNA translation by microRNAs pathway from the Reactome Pathways 2024 dataset. |