Harmonizome 3.0

CTS telomere maintenance complex component 1

This gene encodes a component of the CST complex. This complex plays an essential role in protecting telomeres from degradation. This protein also forms a heterodimer with the CST complex subunit STN1 to form the enzyme alpha accessory factor. This enzyme regulates DNA replication. Mutations in this gene are the cause of cerebroretinal microangiopathy with calcifications and cysts. Alternate splicing results in both coding and non-coding variants. [provided by RefSeq, Mar 2012]

transfer RNA-Glu (CTC) 1-7

transfer RNA-Glu (CTC) 1-1

transfer RNA-Glu (CTC) 1-2

transfer RNA-Glu (CTC) 1-4

transfer RNA-Glu (CTC) 1-6

transfer RNA-Glu (CTC) 1-5

transfer RNA-Glu (CTC) 1-3

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term ctc1 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

From Pathway Commons Protein-Protein Interactions

interacting proteins for CTC1 from the Pathway Commons Protein-Protein Interactions dataset.

From CM4AI KOLF21J CRISPRi Gene Perturbation Atlas

genes differentially expressed following the CTC1 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the CST complex subunit CTC1 protein domain from the InterPro Predicted Protein Domain Annotations dataset.