Name

CXCL11 Gene

chemokine (C-X-C motif) ligand 11

Chemokines are a group of small (approximately 8 to 14 kD), mostly basic, structurally related molecules that regulate cell trafficking of various types of leukocytes through interactions with a subset of 7-transmembrane, G protein-coupled receptors. Chemokines also play fundamental roles in the development, homeostasis, and function of the immune system, and they have effects on cells of the central nervous system as well as on endothelial cells involved in angiogenesis or angiostasis. Chemokines are divided into 2 major subfamilies, CXC and CC. This antimicrobial gene is a CXC member of the chemokine superfamily. Its encoded protein induces a chemotactic response in activated T-cells and is the dominant ligand for CXC receptor-3. The gene encoding this protein contains 4 exons and at least three polyadenylation signals which might reflect cell-specific regulation of expression. IFN-gamma is a potent inducer of transcription of this gene. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2014]

cxcl11 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term cxcl11 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

CXCL11 Gene Set

From Guide to Pharmacology Protein Ligands of Receptors

receptors of the CXCL11 ligand (protein) from the curated Guide to Pharmacology Protein Ligands of Receptors dataset.

CXCL11 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for CXCL11 from the Pathway Commons Protein-Protein Interactions dataset.

CXCL11 Gene Set

From LINCS L1000 CMAP CRISPR Knockout Consensus Signatures

genes differentially expressed following the CXCL11 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

CXCL11 Gene Set

From DGIdb Drug Targets 2026

interacting proteins for the CXCL11 drug from theDGIdb Drug Targets 2026 dataset.

[125I]CXCL11 Gene Set

From Guide to Pharmacology Chemical Ligands of Receptors

receptors of the [125I]CXCL11 ligand (chemical) from the curated Guide to Pharmacology Chemical Ligands of Receptors dataset.

[125I]CXCL11 (HUMAN) Gene Set

From DGIdb Drug Targets 2026

interacting proteins for the [125I]CXCL11 (HUMAN) drug from theDGIdb Drug Targets 2026 dataset.