Name

CYTH3 Gene

cytohesin 3

This gene encodes a member of the PSCD (pleckstrin homology, Sec7 and coiled-coil domains) family. PSCD family members have identical structural organization that consists of an N-terminal coiled-coil motif, a central Sec7 domain, and a C-terminal pleckstrin homology (PH) domain. The coiled-coil motif is involved in homodimerization, the Sec7 domain contains guanine-nucleotide exchange protein (GEP) activity, and the PH domain interacts with phospholipids and is responsible for association of PSCDs with membranes. Members of this family appear to mediate the regulation of protein sorting and membrane trafficking. This encoded protein is involved in the control of Golgi structure and function, and it may have a physiological role in regulating ADP-ribosylation factor protein 6 (ARF) functions, in addition to acting on ARF1. [provided by RefSeq, Jul 2008]

CYTH3 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for CYTH3 from the Pathway Commons Protein-Protein Interactions dataset.

CYTH3 Gene Set

From CM4AI KOLF21J CRISPRi Gene Perturbation Atlas

genes differentially expressed following the CYTH3 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

EPI-1759-1 (CYTH3) Gene Set

From NURSA Protein Complexes

proteins in the EPI-1759-1 (CYTH3) protein complex recovered by IP-MS from the NURSA Protein Complexes dataset.