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TARDBP GeneTAR DNA binding protein HIV-1, the causative agent of acquired immunodeficiency syndrome (AIDS), contains an RNA genome that produces a chromosomally integrated DNA during the replicative cycle. Activation of HIV-1 gene expression by the transactivator Tat is dependent on an RNA regulatory element (TAR) located downstream of the transcription initiation site. The protein encoded by this gene is a transcriptional repressor that binds to chromosomally integrated TAR DNA and represses HIV-1 transcription. In addition, this protein regulates alternate splicing of the CFTR gene. A similar pseudogene is present on chromosome 20. [provided by RefSeq, Jul 2008] |
Ftld-Tdp, Tardbp-Related Gene SetFrom DisGeNET Gene-Disease Associations genes associated with the disease Ftld-Tdp, Tardbp-Related in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset. |
ftld Gene SetFrom GeneRIF Biological Term Annotations genes co-occuring with the biological term ftld in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset. |
FTLD; ALS Gene SetFrom PhosphoSitePlus Phosphosite-Disease Associations proteins associated with the disease FTLD; ALS from the curated PhosphoSitePlus Phosphosite-Disease Associations dataset. |
FTLD Gene SetFrom PhosphoSitePlus Phosphosite-Disease Associations proteins associated with the disease FTLD from the curated PhosphoSitePlus Phosphosite-Disease Associations dataset. |
Alzheimer's disease; FTLD Gene SetFrom PhosphoSitePlus Phosphosite-Disease Associations proteins associated with the disease Alzheimer's disease; FTLD from the curated PhosphoSitePlus Phosphosite-Disease Associations dataset. |
tardbp Gene SetFrom GeneRIF Biological Term Annotations genes co-occuring with the biological term tardbp in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset. |
TARDBP Gene SetFrom Pathway Commons Protein-Protein Interactions interacting proteins for TARDBP from the Pathway Commons Protein-Protein Interactions dataset. |
TARDBP Gene SetFrom CM4AI KOLF21J CRISPRi Gene Perturbation Atlas genes differentially expressed following the TARDBP gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas. |