Glypican-3

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Results for "Glypican-3": 6 genes, 10 gene sets

Name
GPC1 Gene glypican 1 Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation. [provided by RefSeq, Jul 2008]
GPC2 Gene glypican 2 Predicted to be involved in several processes, including positive regulation of neuron projection development; regulation of protein localization to membrane; and smoothened signaling pathway. Located in endoplasmic reticulum. [provided by Alliance of Genome Resources, Mar 2025]
GPC3 Gene glypican 3 Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation. The protein encoded by this gene can bind to and inhibit the dipeptidyl peptidase activity of CD26, and it can induce apoptosis in certain cell types. Deletion mutations in this gene are associated with Simpson-Golabi-Behmel syndrome, also known as Simpson dysmorphia syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2009]
GPC4 Gene glypican 4 Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation. The GPC4 gene is adjacent to the 3' end of GPC3 and may also play a role in Simpson-Golabi-Behmel syndrome. [provided by RefSeq, Jul 2008]
GPC5 Gene glypican 5 Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation. [provided by RefSeq, Jul 2008]
GPC6 Gene glypican 6 The glypicans comprise a family of glycosylphosphatidylinositol-anchored heparan sulfate proteoglycans, and they have been implicated in the control of cell growth and cell division. The glypican encoded by this gene is a putative cell surface coreceptor for growth factors, extracellular matrix proteins, proteases and anti-proteases. Mutations in this gene are associated with omodysplasia 1. [provided by RefSeq, Nov 2016]
Glypican-3 Gene Set From InterPro Predicted Protein Domain Annotations proteins predicted to have the Glypican-3 protein domain from the InterPro Predicted Protein Domain Annotations dataset.
glypican Gene Set From GeneRIF Biological Term Annotations genes co-occuring with the biological term glypican in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.
Glypican Gene Set From InterPro Predicted Protein Domain Annotations proteins predicted to have the Glypican protein domain from the InterPro Predicted Protein Domain Annotations dataset.
Glypican, conserved site Gene Set From InterPro Predicted Protein Domain Annotations proteins predicted to have the Glypican, conserved site protein domain from the InterPro Predicted Protein Domain Annotations dataset.
Glypican-1 Gene Set From InterPro Predicted Protein Domain Annotations proteins predicted to have the Glypican-1 protein domain from the InterPro Predicted Protein Domain Annotations dataset.
Glypican 3 network Gene Set From PID Pathways proteins participating in the Glypican 3 network pathway from the PID Pathways dataset.
Glypican 2 network Gene Set From PID Pathways proteins participating in the Glypican 2 network pathway from the PID Pathways dataset.
Glypican pathway Gene Set From PID Pathways proteins participating in the Glypican pathway pathway from the PID Pathways dataset.
Glypican 1 network Gene Set From PID Pathways proteins participating in the Glypican 1 network pathway from the PID Pathways dataset.
ANTI-GLYPICAN 3/CD3 BISPECIFIC ANTIBODY ERY974 Gene Set From DGIdb Drug Targets 2026 interacting proteins for the ANTI-GLYPICAN 3/CD3 BISPECIFIC ANTIBODY ERY974 drug from theDGIdb Drug Targets 2026 dataset.