Name

LOXL4 Gene

lysyl oxidase-like 4

This gene encodes a member of the lysyl oxidase gene family. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyses the first step in the formation of crosslinks in collagens and elastin. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family. [provided by RefSeq, Jul 2008]

loxl4 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term loxl4 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

LOXL4 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for LOXL4 from the Pathway Commons Protein-Protein Interactions dataset.

Interactions between LOXL4 and oxidative stress pathway Gene Set

From WikiPathways Pathways 2024

proteins participating in the Interactions between LOXL4 and oxidative stress pathway pathway from the WikiPathways Pathways 2024 dataset.