Harmonizome 3.0

melanocortin 2 receptor accessory protein 2

This gene encodes a protein that modulates melanocortin receptor signaling. The encoded protein has been shown to interact with all known melanocortin receptors and may regulate both receptor trafficking and activation in response to ligands. Mice lacking a functional copy of this gene exhibit severe obesity and a mutation in this gene may be associated with severe obesity in human patients. [provided by RefSeq, Oct 2016]

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term mrap2 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

From Pathway Commons Protein-Protein Interactions

interacting proteins for MRAP2 from the Pathway Commons Protein-Protein Interactions dataset.