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MUC20 Genemucin 20, cell surface associated This gene encodes a member of the mucin protein family. Mucins are high molecular weight glycoproteins secreted by many epithelial tissues to form an insoluble mucous barrier. The C-terminus of this family member associates with the multifunctional docking site of the MET proto-oncogene and suppresses activation of some downstream MET signaling cascades. The protein features a mucin tandem repeat domain that varies between two and six copies in most individuals. Multiple variants encoding different isoforms have been found for this gene. A related pseudogene, which is also located on chromosome 3, has been identified. [provided by RefSeq, Apr 2014] |
muc20 Gene SetFrom GeneRIF Biological Term Annotations genes co-occuring with the biological term muc20 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset. |
MUC20 Gene SetFrom Pathway Commons Protein-Protein Interactions interacting proteins for MUC20 from the Pathway Commons Protein-Protein Interactions dataset. |
MUC20 Gene SetFrom LINCS L1000 CMAP CRISPR Knockout Consensus Signatures genes differentially expressed following the MUC20 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset. |