Name

MX1 Gene

MX dynamin-like GTPase 1

This gene encodes a guanosine triphosphate (GTP)-metabolizing protein that participates in the cellular antiviral response. The encoded protein is induced by type I and type II interferons and antagonizes the replication process of several different RNA and DNA viruses. There is a related gene located adjacent to this gene on chromosome 21, and there are multiple pseudogenes located in a cluster on chromosome 4. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]

mx1 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term mx1 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

MX1 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for MX1 from the Pathway Commons Protein-Protein Interactions dataset.

MX1 Gene Set

From LINCS L1000 CMAP CRISPR Knockout Consensus Signatures

genes differentially expressed following the MX1 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.