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PACS2 Genephosphofurin acidic cluster sorting protein 2 Predicted to enable transmembrane transporter binding activity. Involved in endoplasmic reticulum calcium ion homeostasis; mitochondrion-endoplasmic reticulum membrane tethering; and protein localization to plasma membrane. Acts upstream of or within protein localization to phagophore assembly site. Located in endoplasmic reticulum and mitochondrion. Implicated in developmental and epileptic encephalopathy 66. [provided by Alliance of Genome Resources, Mar 2025] |
pacs2 Gene SetFrom GeneRIF Biological Term Annotations genes co-occuring with the biological term pacs2 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset. |
PACS2 Gene SetFrom Pathway Commons Protein-Protein Interactions interacting proteins for PACS2 from the Pathway Commons Protein-Protein Interactions dataset. |
PACS2 Gene SetFrom CM4AI KOLF21J CRISPRi Gene Perturbation Atlas genes differentially expressed following the PACS2 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas. |