Harmonizome 3.0

phosphatidylinositol 3-kinase, catalytic subunit type 3

Enables 1-phosphatidylinositol-3-kinase activity. Involved in several processes, including early endosome to late endosome transport; macroautophagy; and phosphatidylinositol-3-phosphate biosynthetic process. Acts upstream of or within autophagy and positive regulation of protein lipidation. Located in autolysosome; late endosome; and midbody. Part of phosphatidylinositol 3-kinase complex, class III. [provided by Alliance of Genome Resources, Mar 2025]

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term pik3c3 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

From NURSA Protein-Protein Interactions

interacting proteins for PIK3C3 from the NURSA Protein-Protein Interactions dataset.

From Pathway Commons Protein-Protein Interactions

interacting proteins for PIK3C3 from the Pathway Commons Protein-Protein Interactions dataset.

From LINCS L1000 CMAP CRISPR Knockout Consensus Signatures

genes differentially expressed following the PIK3C3 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

From CORUM Protein Complexes

proteins in the Phosphatidylinositol 3-kinase complex (PIK3C3, PIK3R4) protein complex from the CORUM Protein Complexes dataset.