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Results for "PRDM12": 1 gene, 3 gene sets

Name

PRDM12 Gene

PR domain containing 12

This gene encodes a transcriptional regulator of sensory neuronal specification that plays a critical role in pain perception. The encoded protein contains an N-terminal PRDI-BF1 and RIZ homology (PR) domain, a SET domain, and three C-terminal C2H2 zinc finger DNA-binding domains. Naturally occurring mutations in this gene are associated with congenital insensitivity to pain (CIP), and hereditary sensory and autonomic neuropathies (HSAN's) affecting peripheral sensory and autonomic neurons. Deregulation of this gene is associated with solid cancers and hematological malignancies including chronic myeloid leukaemia. [provided by RefSeq, Mar 2017]

PRDM12 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for PRDM12 from the Pathway Commons Protein-Protein Interactions dataset.

PRDM12 Gene Set

From CM4AI KOLF21J CRISPRi Gene Perturbation Atlas

genes differentially expressed following the PRDM12 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

PR-domain zinc finger protein PRDM12 Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the PR-domain zinc finger protein PRDM12 protein domain from the InterPro Predicted Protein Domain Annotations dataset.