Harmonizome 3.0

RAB27A, member RAS oncogene family

The protein encoded by this gene belongs to the small GTPase superfamily, Rab family. The protein is membrane-bound and may be involved in protein transport and small GTPase mediated signal transduction. Mutations in this gene are associated with Griscelli syndrome type 2. Alternative splicing occurs at this locus and four transcript variants encoding the same protein have been identified. [provided by RefSeq, Jul 2008]

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term rab27a in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

From Pathway Commons Protein-Protein Interactions

interacting proteins for RAB27A from the Pathway Commons Protein-Protein Interactions dataset.

From LINCS L1000 CMAP CRISPR Knockout Consensus Signatures

genes differentially expressed following the RAB27A gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

From CORUM Protein Complexes

proteins in the Rab27A-Melanophilin-MyosinVa complex protein complex from the CORUM Protein Complexes dataset.

From CORUM Protein Complexes

proteins in the Rab27a-melanophilin-myosin-Va complex protein complex from the CORUM Protein Complexes dataset.

From CORUM Protein Complexes

proteins in the Rab27a-Mlph-Myo5a complex protein complex from the CORUM Protein Complexes dataset.

From CORUM Protein Complexes

proteins in the Slp5-Rab27A complex protein complex from the CORUM Protein Complexes dataset.