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SAT1 Genespermidine/spermine N1-acetyltransferase 1 The protein encoded by this gene belongs to the acetyltransferase family, and is a rate-limiting enzyme in the catabolic pathway of polyamine metabolism. It catalyzes the acetylation of spermidine and spermine, and is involved in the regulation of the intracellular concentration of polyamines and their transport out of cells. Defects in this gene are associated with keratosis follicularis spinulosa decalvans (KFSD). Alternatively spliced transcripts have been found for this gene.[provided by RefSeq, Sep 2009] |
sat1 Gene SetFrom GeneRIF Biological Term Annotations genes co-occuring with the biological term sat1 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset. |
SAT1 Gene SetFrom Pathway Commons Protein-Protein Interactions interacting proteins for SAT1 from the Pathway Commons Protein-Protein Interactions dataset. |
SAT1 Gene SetFrom CM4AI KOLF21J CRISPRi Gene Perturbation Atlas genes differentially expressed following the SAT1 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas. |