Harmonizome 3.0

SET and MYND domain containing 1

Predicted to enable several functions, including histone H3K4 trimethyltransferase activity; metal ion binding activity; and transcription corepressor activity. Involved in positive regulation of myoblast differentiation and positive regulation of myotube differentiation. Predicted to be located in cytoplasm. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Mar 2025]

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term smyd1 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

From Pathway Commons Protein-Protein Interactions

interacting proteins for SMYD1 from the Pathway Commons Protein-Protein Interactions dataset.

From LINCS L1000 CMAP CRISPR Knockout Consensus Signatures

genes differentially expressed following the SMYD1 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.

From CM4AI KOLF21J CRISPRi Gene Perturbation Atlas

genes differentially expressed following the SMYD1 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

From HuBMAP Azimuth Cell Type Annotations

genes associated with the Human - Motor Cortex - Cluster - THEMIS+ SMYD1+ Layer 5-6 glutamatergic neuron cell type from the HuBMAP Azimuth Cell Type Annotations dataset.

From HuBMAP ASCT+B Annotations

biomarker genes for the Brain_CT2_Exc L5-6 THEMIS SMYD1 cell type from the HuBMAP ASCT+B dataset.

From HuBMAP ASCT+B Augmented with RNA-seq Coexpression

biomarker genes for the Brain_CT2_Exc L5-6 THEMIS SMYD1 cell type from the HuBMAP ASCT+B Augmented with RNA-seq Coexpression dataset.