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SYCE1 Genesynaptonemal complex central element protein 1 This gene encodes a member of the synaptonemal complex, which links homologous chromosomes during prophase I of meiosis. The tripartite structure of the complex is highly conserved amongst metazoans. It consists of two lateral elements and a central region formed by transverse elements and a central element. The protein encoded by this gene localizes to the central element and is required for initiation and elongation of the synapsis. Allelic variants of this gene have been associated with premature ovarian failure and spermatogenic failure. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2016] |
SYCE1 Gene SetFrom Pathway Commons Protein-Protein Interactions interacting proteins for SYCE1 from the Pathway Commons Protein-Protein Interactions dataset. |
Sycp1-Syce1-Syce2 complex Gene Setproteins in the Sycp1-Syce1-Syce2 complex protein complex from the CORUM Protein Complexes dataset. |