Harmonizome 3.0

tachykinin 3

This gene encodes a member of the tachykinin family of secreted neuropeptides. The encoded preproprotein is proteolytically processed to generate the mature peptide, which is primarily expressed in the central and peripheral nervous systems and functions as a neurotransmitter. This peptide is the ligand for the neurokinin-3 receptor. This protein is also expressed in the outer syncytiotrophoblast of the placenta and may be associated with pregnancy-induced hypertension and pre-eclampsia. Mutations in this gene are associated with normosmic hypogonadotropic hypogonadism. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Feb 2016]

transfer RNA-Val (TAC) 3-1

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term tac3 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

From Guide to Pharmacology Protein Ligands of Receptors

receptors of the TAC3 ligand (protein) from the curated Guide to Pharmacology Protein Ligands of Receptors dataset.

From Pathway Commons Protein-Protein Interactions

interacting proteins for TAC3 from the Pathway Commons Protein-Protein Interactions dataset.

From CM4AI KOLF21J CRISPRi Gene Perturbation Atlas

genes differentially expressed following the TAC3 gene perturbation from the CM4AI KOLF21J CRISPRi Gene Perturbation Atlas.

From HuBMAP Azimuth Cell Type Annotations

genes associated with the Human - Motor Cortex - Cluster - VIP+ TAC3+ Layer 3-5 GABAergic neuron cell type from the HuBMAP Azimuth Cell Type Annotations dataset.

From HuBMAP ASCT+B Annotations

biomarker genes for the Brain_CT2_Inh L3-5 VIP TAC3 cell type from the HuBMAP ASCT+B dataset.

From HuBMAP ASCT+B Augmented with RNA-seq Coexpression

biomarker genes for the Brain_CT2_Inh L3-5 VIP TAC3 cell type from the HuBMAP ASCT+B Augmented with RNA-seq Coexpression dataset.