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Results for "TDO2": 1 gene, 2 gene sets

Name

TDO2 Gene

tryptophan 2,3-dioxygenase

This gene encodes a heme enzyme that plays a critical role in tryptophan metabolism by catalyzing the first and rate-limiting step of the kynurenine pathway. Increased activity of the encoded protein and subsequent kynurenine production may also play a role in cancer through the suppression of antitumor immune responses, and single nucleotide polymorphisms in this gene may be associated with autism. [provided by RefSeq, Feb 2012]

TDO2 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for TDO2 from the Pathway Commons Protein-Protein Interactions dataset.

TDO2 Gene Set

From LINCS L1000 CMAP CRISPR Knockout Consensus Signatures

genes differentially expressed following the TDO2 gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.