Filters:

Results for "Thiopurine S-methyltransferase": 5 genes, 17 gene sets

Name

TPMTP1 Gene

thiopurine S-methyltransferase pseudogene 1

TPMTP3 Gene

thiopurine S-methyltransferase pseudogene 3

TPMTP2 Gene

thiopurine S-methyltransferase pseudogene 2

TPMTP4 Gene

thiopurine S-methyltransferase pseudogene 4

TPMT Gene

thiopurine S-methyltransferase

This gene encodes the enzyme that metabolizes thiopurine drugs via S-adenosyl-L-methionine as the S-methyl donor and S-adenosyl-L-homocysteine as a byproduct. Thiopurine drugs such as 6-mercaptopurine are used as chemotherapeutic agents. Genetic polymorphisms that affect this enzymatic activity are correlated with variations in sensitivity and toxicity to such drugs within individuals, causing thiopurine S-methyltransferase deficiency. Related pseudogenes have been identified on chromosomes 3, 18 and X. [provided by RefSeq, Aug 2014]

Thiopurine S-methyltransferase Gene Set

From InterPro Predicted Protein Domain Annotations

proteins predicted to have the Thiopurine S-methyltransferase protein domain from the InterPro Predicted Protein Domain Annotations dataset.

Thiopurine S methyltranferase deficiency Gene Set

From CTD Gene-Disease Associations

genes/proteins associated with the disease Thiopurine S methyltranferase deficiency from the curated CTD Gene-Disease Associations dataset.

thiopurine toxicity Gene Set

From GAD Gene-Disease Associations

genes associated with the disease thiopurine toxicity in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

thiopurine Gene Set

From GAD Gene-Disease Associations

genes associated with the disease thiopurine in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

thiopurine s-methytransferase activity Gene Set

From GAD Gene-Disease Associations

genes associated with the disease thiopurine s-methytransferase activity in GWAS and other genetic association datasets from the GAD Gene-Disease Associations dataset.

thiopurine Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term thiopurine in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

Thiopurine S Methyltranferase Deficiency Gene Set

From DisGeNET Gene-Disease Associations

genes associated with the disease Thiopurine S Methyltranferase Deficiency in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Thiopurine-induced myelosuppression in inflammatory bowel disease Gene Set

From GWAS Catalog SNP-Phenotype Associations 2025

genes associated with the Thiopurine-induced myelosuppression in inflammatory bowel disease phenotype in GWAS datasets from the GWAS Catalog SNP-Phenotype Associations 2025 dataset.

Thiopurine-induced early leukopenia in Crohn's disease Gene Set

From GWAS Catalog SNP-Phenotype Associations 2025

genes associated with the Thiopurine-induced early leukopenia in Crohn's disease phenotype in GWAS datasets from the GWAS Catalog SNP-Phenotype Associations 2025 dataset.

Thiopurine-induced leukopenia in inflammatory bowel disease Gene Set

From GWAS Catalog SNP-Phenotype Associations 2025

genes associated with the Thiopurine-induced leukopenia in inflammatory bowel disease phenotype in GWAS datasets from the GWAS Catalog SNP-Phenotype Associations 2025 dataset.

Thiopurine-induced leukopenia in inflammatory bowel disease (conditioned on rs116855232) Gene Set

From GWAS Catalog SNP-Phenotype Associations 2025

genes associated with the Thiopurine-induced leukopenia in inflammatory bowel disease (conditioned on rs116855232) phenotype in GWAS datasets from the GWAS Catalog SNP-Phenotype Associations 2025 dataset.

Thiopurine-induced severe leukopenia in inflammatory bowel disease Gene Set

From GWAS Catalog SNP-Phenotype Associations 2025

genes associated with the Thiopurine-induced severe leukopenia in inflammatory bowel disease phenotype in GWAS datasets from the GWAS Catalog SNP-Phenotype Associations 2025 dataset.

Thiopurine-induced acute severe leukopenia in inflammatory bowel disease Gene Set

From GWAS Catalog SNP-Phenotype Associations 2025

genes associated with the Thiopurine-induced acute severe leukopenia in inflammatory bowel disease phenotype in GWAS datasets from the GWAS Catalog SNP-Phenotype Associations 2025 dataset.

Thiopurine-induced alopecia in inflammatory bowel disease Gene Set

From GWAS Catalog SNP-Phenotype Associations 2025

genes associated with the Thiopurine-induced alopecia in inflammatory bowel disease phenotype in GWAS datasets from the GWAS Catalog SNP-Phenotype Associations 2025 dataset.

Thiopurine-induced severe alopecia in inflammatory bowel disease Gene Set

From GWAS Catalog SNP-Phenotype Associations 2025

genes associated with the Thiopurine-induced severe alopecia in inflammatory bowel disease phenotype in GWAS datasets from the GWAS Catalog SNP-Phenotype Associations 2025 dataset.

Thiopurine-induced pancreatitis in inflammatory bowel disease Gene Set

From GWAS Catalog SNP-Phenotype Associations 2025

genes associated with the Thiopurine-induced pancreatitis in inflammatory bowel disease phenotype in GWAS datasets from the GWAS Catalog SNP-Phenotype Associations 2025 dataset.

Thiopurine-induced digestive symptoms in inflammatory bowel disease Gene Set

From GWAS Catalog SNP-Phenotype Associations 2025

genes associated with the Thiopurine-induced digestive symptoms in inflammatory bowel disease phenotype in GWAS datasets from the GWAS Catalog SNP-Phenotype Associations 2025 dataset.