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Results for "march2": 1 gene, 2 gene sets

Name

MARCH2 Gene

membrane-associated ring finger (C3HC4) 2, E3 ubiquitin protein ligase

MARCH2 is a member of the MARCH family of membrane-bound E3 ubiquitin ligases (EC 6.3.2.19). MARCH enzymes add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments. MARCH2 reduces surface accumulation of several glycoproteins and appears to regulate early endosome-to-trans-Golgi network (TGN) trafficking (Bartee et al., 2004 [PubMed 14722266]; Nakamura et al., 2005 [PubMed 15689499]).[supplied by OMIM, Mar 2010]

march2 Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term march2 in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

MARCH2 Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for MARCH2 from the Pathway Commons Protein-Protein Interactions dataset.