Name

MARCO Gene

macrophage receptor with collagenous structure

The protein encoded by this gene is a member of the class A scavenger receptor family and is part of the innate antimicrobial immune system. The protein may bind both Gram-negative and Gram-positive bacteria via an extracellular, C-terminal, scavenger receptor cysteine-rich (SRCR) domain. In addition to short cytoplasmic and transmembrane domains, there is an extracellular spacer domain and a long, extracellular collagenous domain. The protein may form a trimeric molecule by the association of the collagenous domains of three identical polypeptide chains. [provided by RefSeq, Jul 2008]

marco Gene Set

From GeneRIF Biological Term Annotations

genes co-occuring with the biological term marco in literature-supported statements describing functions of genes from the GeneRIF Biological Term Annotations dataset.

MARCO Gene Set

From Pathway Commons Protein-Protein Interactions

interacting proteins for MARCO from the Pathway Commons Protein-Protein Interactions dataset.

MARCO Gene Set

From LINCS L1000 CMAP CRISPR Knockout Consensus Signatures

genes differentially expressed following the MARCO gene perturbation from the LINCS L1000 CMAP CRISPR Knockout Consensus Signatures dataset.